› 6lu9

Electron Microscopy
8.8Å resolution

Rat ionotropic Glutamate Delta-2 receptor in complex with 7-CKA and Calcium

Released:
DOI: 10.2210/pdb6lu9/pdb
PDB entry 6lu9 coloured by chain, front view.
PDB entry 6lu9 coloured by chain, side view.
PDB entry 6lu9 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
The architecture of GluD2 ionotropic delta glutamate receptor elucidated by cryo-EM.
Burada AP, Vinnakota R, Kumar J
J Struct Biol 211 107546 (2020)
PMID: 32512155
Related structures: EMD-0979

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179002 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, delta-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 877 amino acids
Theoretical weight: 98.69 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q63226 (Residues: 24-893; Coverage: 88%)
Gene name: Grid2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 8.8Å
Relevant EMDB volumes: EMD-0979
Expression system: Homo sapiens

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Citations

4 review citations

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
3 more

1 mention without citation

Delta glutamate receptors are functional glycine- and ᴅ-serine-gated cation channels in situ.
Carrillo et al. (2021)