Function and Biology Details
Reaction catalysed:
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123578 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Uracil-DNA glycosylase
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 255 amino acids
Theoretical weight: 29.05 KDa
Source organism: Human gammaherpesvirus 8
Expression system: Escherichia coli
UniProt:
Sequence domains: Uracil DNA glycosylase superfamily
Length: 255 amino acids
Theoretical weight: 29.05 KDa
Source organism: Human gammaherpesvirus 8
Expression system: Escherichia coli
UniProt:
- Canonical:
F5HFA1 (Residues: 1-255; Coverage: 100%)
Sequence domains: Uracil DNA glycosylase superfamily
SAUGI
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 112 amino acids
Theoretical weight: 13.37 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Length: 112 amino acids
Theoretical weight: 13.37 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical: Q936H5 (Residues: 1-112; Coverage: 100%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSRRC BEAMLINE BL13C1
Spacegroup:
P1
Expression system: Escherichia coli
