6m02

Electron Microscopy
3.2Å resolution

cryo-EM structure of human Pannexin 1 channel

Released:
Source organism: Homo sapiens
Primary publication:
Cryo-EM structure of human heptameric Pannexin 1 channel.
Cell Res 30 446-448 (2020)
PMID: 32203128
Related structures: EMD-30028

Function and Biology Details

Biochemical function:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188716 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pannexin-1 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 426 amino acids
Theoretical weight: 48.09 KDa
Source organism: Homo sapiens
Expression system: Eukaryota sp.
UniProt:
  • Canonical: Q96RD7 (Residues: 1-426; Coverage: 100%)
Gene names: MRS1, PANX1, UNQ2529/PRO6028
Sequence domains: Innexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-30028
Expression system: Eukaryota sp.