Function and Biology Details
Reaction catalysed:
Degradation of blood coagulation factors Va and VIIIa.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Active Protein C complex and antibody (preferred)
PDBe Complex ID:
PDB-CPX-279495 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Vitamin K-dependent protein C heavy chain
Molecule details ›
Chains: A, C, G
Length: 250 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Trypsin
Length: 250 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P04070 (Residues: 212-461; Coverage: 56%)
Sequence domains: Trypsin
Vitamin K-dependent protein C light chain
Molecule details ›
Chains: B, D, I
Length: 155 amino acids
Theoretical weight: 17.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 155 amino acids
Theoretical weight: 17.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P04070 (Residues: 43-197; Coverage: 35%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
SSRF BEAMLINE BL17U1
Spacegroup:
P43212
Expression systems:
- Homo sapiens
- Cricetulus griseus
