› 6me9

X-ray diffraction
3.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132347 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Melatonin receptor type 1B; Rubredoxin; Soluble cytochrome b562 Chains: A, B
Molecule details ›
Chains: A, B
Length: 460 amino acids
Theoretical weight: 51.51 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
  • Canonical: P49286 (Residues: 35-231, 241-340; Coverage: 82%)
  • Canonical: P00268 (Residues: 1-53; Coverage: 98%)
Gene names: MTNR1B, cybC
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand JEV 2 x JEV
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLAC LCLS BEAMLINE CXI
Spacegroup: P21
Unit cell:
a: 69.4Å b: 145.7Å c: 77.2Å
α: 90° β: 106.2° γ: 90°
R-values:
R R work R free
0.249 0.248 0.27
Expression system: Spodoptera frugiperda

Quick links

Citations

13 review citations

Melatonin Target Proteins: Too Many or Not Enough?
Liu et al. (2019)
12 more

8 mentions without citation

G protein-coupled receptors: structure- and function-based drug discovery.
Yang et al. (2021)
7 more