› 6mew

X-ray diffraction
1.78Å resolution

RFXANK ankyrin repeats in complex with a RFX7 peptide

Released:
DOI: 10.2210/pdb6mew/pdb
PDB entry 6mew coloured by chain, front view.
PDB entry 6mew coloured by chain, side view.
PDB entry 6mew coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tempel W, Xu C, Dong A, Li Y, Bountra C, Arrowsmith CH, Edwards AM, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127016 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA-binding protein RFXANK Chains: A, C
Molecule details ›
Chains: A, C
Length: 172 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14593 (Residues: 90-260; Coverage: 66%)
Gene names: ANKRA1, RFXANK, RFXB
Sequence domains: Ankyrin repeat
Structure domains: Ankyrin repeat-containing domain
DNA-binding protein RFX7 Chains: B, D
Molecule details ›
Chains: B, D
Length: 17 amino acids
Theoretical weight: 2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q2KHR2 (Residues: 182-198; Coverage: 1%)
Gene names: RFX7, RFXDC2

Ligands and Environments

1 bound ligand:
Ligand UNX 53 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P21
Unit cell:
a: 64.23Å b: 29.87Å c: 97.89Å
α: 90° β: 102.12° γ: 90°
R-values:
R R work R free
0.178 0.176 0.219
Expression systems:
  • Escherichia coli BL21
  • Not provided

Quick links