Function and Biology Details
Reaction catalysed:
N-acylsphingosine + H(2)O = a carboxylate + sphingosine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Acid ceramidase subunit beta (preferred)
PDBe Complex ID:
PDB-CPX-171732 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Acid ceramidase subunit alpha
Molecule details ›
Chains: A, C
Length: 131 amino acids
Theoretical weight: 15.08 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains: beta subunit of N-acylethanolamine-hydrolyzing acid amidase
Length: 131 amino acids
Theoretical weight: 15.08 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical:
Q13510 (Residues: 22-142; Coverage: 32%)
Sequence domains: beta subunit of N-acylethanolamine-hydrolyzing acid amidase
Acid ceramidase subunit beta
Molecule details ›
Chains: B, D
Length: 253 amino acids
Theoretical weight: 28.99 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains: Linear amide C-N hydrolases, choloylglycine hydrolase family
Length: 253 amino acids
Theoretical weight: 28.99 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical: Q13510 (Residues: 143-395; Coverage: 68%)
Sequence domains: Linear amide C-N hydrolases, choloylglycine hydrolase family
Ligands and Environments
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-BM
Spacegroup:
C2
Expression system: unidentified baculovirus
