› 6mhv

Electron Microscopy
3.5Å resolution

Structure of human TRPV3 in the presence of 2-APB in C4 symmetry

Released:
DOI: 10.2210/pdb6mhv/pdb
PDB entry 6mhv coloured by chain, front view.
PDB entry 6mhv coloured by chain, side view.
PDB entry 6mhv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conformational ensemble of the human TRPV3 ion channel.
Zubcevic L, Herzik MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun 9 4773 (2018)
PMID: 30429472
Related structures: EMD-9119

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185515 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transient receptor potential cation channel subfamily V member 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 826 amino acids
Theoretical weight: 94.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8NET8 (Residues: 2-790; Coverage: 100%)
Gene name: TRPV3
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-9119
Expression system: Spodoptera frugiperda

Quick links

Citations

16 review citations

Transient Receptor Potential Channels and Calcium Signaling.
Vangeel et al. (2019)
15 more

3 mentions without citation

Structural insights into the gating mechanisms of TRPV channels.
Pumroy et al. (2020)
2 more