› 6mky

X-ray diffraction
2.9Å resolution

Human SDS22

Released:
DOI: 10.2210/pdb6mky/pdb
PDB entry 6mky coloured by chain, front view.
PDB entry 6mky coloured by chain, side view.
PDB entry 6mky coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of SDS22 provides insights into the mechanism of heterodimer formation with PP1.
Choy MS, Bolik-Coulon N, Archuleta TL, Peti W, Page R
Acta Crystallogr F Struct Biol Commun 74 817-824 (2018)
PMID: 30511677

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172288 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein phosphatase 1 regulatory subunit 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 261 amino acids
Theoretical weight: 30.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15435 (Residues: 100-360; Coverage: 73%)
Gene names: PPP1R7, SDS22
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 10 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 75.104Å b: 76.546Å c: 128.283Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.238 0.272
Expression system: Homo sapiens

Quick links

Citations

3 citation in other articles

SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Choy et al. (2019)
2 more

1 mention without citation

The structure of SDS22 provides insights into the mechanism of heterodimer formation with PP1.
Choy et al. (2018)