Function and Biology Details
Reactions catalysed:
Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Lysosomal phospholipase A and acyltransferase (preferred)
PDBe Complex ID:
PDB-CPX-185486 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysosomal phospholipase A and acyltransferase
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 43.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Lecithin:cholesterol acyltransferase
Structure domains: alpha/beta hydrolase
Length: 380 amino acids
Theoretical weight: 43.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q8NCC3 (Residues: 34-412; Coverage: 100%)
Sequence domains: Lecithin:cholesterol acyltransferase
Structure domains: alpha/beta hydrolase
