PDB 6mu4 structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Biochemical function:

metal ion binding

Biological process:

double-strand break repair via alternative nonhomologous end joining

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero trimer (preferred)

Assembly name:

DNA polymerase I and DNA (preferred)

PDBe Complex ID:

PDB-CPX-120304 (preferred)

Entry contents:

1 distinct polypeptide molecule
2 distinct DNA molecules

Macromolecules (3 distinct):

DNA polymerase I Chain: A

Molecule details ›

Chain: A
Length: 577 amino acids
Theoretical weight: 65.9 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli
UniProt:

Canonical: E1C9K5 (Residues: 4-580; Coverage: 100%)

Gene name: polA
Sequence domains: DNA polymerase family A

DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3') Chain: P

Molecule details ›

Chain: P
Length: 11 nucleotides
Theoretical weight: 3.35 KDa
Source organism: synthetic construct
Expression system: Not provided

FANA (5'-D(P*(UF2)P*(A5L)P*(CFL)P*(GFL)P*(UF2)P*(GFL)P*(A5L)P*(UF2)P*(CFL)P*(GFL)P*(CFL))-3') Chain: T

Molecule details ›

Chain: T
Length: 13 nucleotides
Theoretical weight: 4.18 KDa
Source organism: synthetic construct
Expression system: Not provided