› 6n31

X-ray diffraction
2.6Å resolution

WD repeats of human WDR12

Released:
DOI: 10.2210/pdb6n31/pdb
PDB entry 6n31 coloured by chain, front view.
PDB entry 6n31 coloured by chain, side view.
PDB entry 6n31 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Halabelian L, Zeng H, Tempel W, Li Y, Seitova A, Hutchinson A, Bountra C, Edwards AM, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome biogenesis protein WDR12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 351 amino acids
Theoretical weight: 39.3 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9GZL7 (Residues: 90-422; Coverage: 79%)
Gene name: WDR12
Sequence domains: WD domain, G-beta repeat

Ligands and Environments

1 bound ligand:
Ligand UNX 36 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 52.74Å b: 87.05Å c: 155.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.233
Expression system: Spodoptera frugiperda

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