› 6n6j

X-ray diffraction
1.32Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195189 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Oligoribonuclease, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 205 amino acids
Theoretical weight: 23.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y3B8 (Residues: 33-237; Coverage: 87%)
Gene names: CGI-114, REXO2, SFN, SMFN
Sequence domains: Exonuclease
RNA (5'-R(P*AP*A)-3') Chains: C, D
Molecule details ›
Chains: C, D
Length: 2 nucleotides
Theoretical weight: 613 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

4 bound ligands:
Ligand GOL 2 x GOL
Ligand MLI 1 x MLI
Ligand NA 2 x NA
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 45.863Å b: 87.566Å c: 124.225Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.153 0.17
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

4 review citations

Nucleotide second messengers in bacterial decision making.
Thompson et al. (2020)
3 more

3 mentions without citation

A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.
Kim et al. (2019)
2 more