6n9o

X-ray diffraction
3.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-157625 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gasdermin-D Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 485 amino acids
Theoretical weight: 52.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P57764 (Residues: 1-484; Coverage: 100%)
Gene names: DFNA5L, FKSG10, GSDMD, GSDMDC1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 58.64Å b: 105.55Å c: 151.79Å
α: 90° β: 94.47° γ: 90°
R-values:
R R work R free
0.28 0.276 0.345
Expression system: Escherichia coli