6nb4

Electron Microscopy
3.6Å resolution

MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-207344 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (8 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1359 amino acids
Theoretical weight: 149.17 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A140AYW5 (Residues: 19-1294; Coverage: 94%)
Gene name: S
Sequence domains:
LCA60 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 127 amino acids
Theoretical weight: 13.92 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
LCA60 light chain Chain: L
Molecule details ›
Chain: L
Length: 109 amino acids
Theoretical weight: 11.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-0402
Expression system: Homo sapiens