6nb5

X-ray diffraction
3Å resolution

Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-232223 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
LCA60 antigen-binding (Fab) fragment, heavy chain Chains: H, I
Molecule details ›
Chains: H, I
Length: 230 amino acids
Theoretical weight: 24.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
LCA60 antigen-binding (Fab) fragment, light chain Chains: L, M
Molecule details ›
Chains: L, M
Length: 215 amino acids
Theoretical weight: 22.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P21
Unit cell:
a: 70.725Å b: 69.575Å c: 93.838Å
α: 90° β: 107.65° γ: 90°
R-values:
R R work R free
0.231 0.228 0.283
Expression system: Homo sapiens