› 6ndu

X-ray diffraction
2.1Å resolution

Structure of human PACRG-MEIG1 complex

Released:
DOI: 10.2210/pdb6ndu/pdb
PDB entry 6ndu coloured by chain, front view.
PDB entry 6ndu coloured by chain, side view.
PDB entry 6ndu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human PACRG in complex with MEIG1
Khan N, Pelletier D, Veyron S, Croteau N, Ichikawa M, Black C, Khalifa AAZ, Chaaban S, Kurinov I, Brouhard G, Bui KH, Trempe JF
Biorxiv (2019)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177332 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Parkin coregulated gene protein Chain: A
Molecule details ›
Chain: A
Length: 193 amino acids
Theoretical weight: 22.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96M98 (Residues: 70-296; Coverage: 64%)
Gene names: GLUP, PACRG
Sequence domains: Parkin co-regulated protein
Meiosis expressed gene 1 protein homolog Chain: B
Molecule details ›
Chain: B
Length: 93 amino acids
Theoretical weight: 11.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5JSS6 (Residues: 1-88; Coverage: 100%)
Gene name: MEIG1
Sequence domains: Meiosis-expressed

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P41212
Unit cell:
a: 67.297Å b: 67.297Å c: 158.255Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.19 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links