6nf2

Electron Microscopy
3.7Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 24-mer (preferred)
PDBe Complex ID:
PDB-CPX-212145 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (15 distinct):
Transmembrane protein gp41 Chains: A, G, Q
Molecule details ›
Chains: A, G, Q
Length: 480 amino acids
Theoretical weight: 53.93 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-509; Coverage: 56%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chains: B, I, R
Molecule details ›
Chains: B, I, R
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
VRC03 Heavy Chain Chains: C, N, V
Molecule details ›
Chains: C, N, V
Length: 235 amino acids
Theoretical weight: 25.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VRC03 Light Chain Chains: D, M, U
Molecule details ›
Chains: D, M, U
Length: 209 amino acids
Theoretical weight: 23.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT122 Heavy Chain Chains: E, J, S
Molecule details ›
Chains: E, J, S
Length: 235 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT122 Light Chain Chains: F, K, T
Molecule details ›
Chains: F, K, T
Length: 213 amino acids
Theoretical weight: 22.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
0PV-c.01 Heavy Chain Chains: H, O, W
Molecule details ›
Chains: H, O, W
Length: 229 amino acids
Theoretical weight: 24.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
0PV-c.01 Light Chain Chains: L, P, X
Molecule details ›
Chains: L, P, X
Length: 219 amino acids
Theoretical weight: 23.97 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-9359
Expression system: Homo sapiens