› 6nh9

X-ray diffraction
1.85Å resolution

Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain

Released:
DOI: 10.2210/pdb6nh9/pdb
PDB entry 6nh9 coloured by chain, front view.
PDB entry 6nh9 coloured by chain, side view.
PDB entry 6nh9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sun YJ, Gakhar L, Fuentes EJ

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127208 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peripheral plasma membrane protein CASK Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 88 amino acids
Theoretical weight: 10.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14936 (Residues: 485-485, 487-572; Coverage: 9%)
Gene names: CASK, LIN2
Sequence domains: PDZ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: C2
Unit cell:
a: 61.052Å b: 35.4Å c: 119.487Å
α: 90° β: 90.31° γ: 90°
R-values:
R R work R free
0.228 0.226 0.263
Expression system: Escherichia coli

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