› 6nje

X-ray diffraction
2.2Å resolution

Crystal structure of the motor domain of human kinesin family member 22

Released:
DOI: 10.2210/pdb6nje/pdb
PDB entry 6nje coloured by chain, front view.
PDB entry 6nje coloured by chain, side view.
PDB entry 6nje coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker BC, Zhu H, Tempel W, Arrowsmith CH, Edwards AM, Park H, Cochran JC, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172104 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF22 Chain: A
Molecule details ›
Chain: A
Length: 379 amino acids
Theoretical weight: 42.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14807 (Residues: 40-400; Coverage: 54%)
Gene names: KID, KIF22, KNSL4
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

4 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
Ligand CL 3 x CL
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P212121
Unit cell:
a: 44.53Å b: 58.73Å c: 116.453Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.258
Expression system: Escherichia coli

Quick links