› 6ns1

X-ray diffraction
1.85Å resolution

Crystal structure of DIP-gamma IG1+IG2

Released:
DOI: 10.2210/pdb6ns1/pdb
PDB entry 6ns1 coloured by chain, front view.
PDB entry 6ns1 coloured by chain, side view.
PDB entry 6ns1 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Cheng S, Ashley J, Kurleto JD, Lobb-Rabe M, Park YJ, Carrillo RA, Özkan E
Elife 8 (2019)
PMID: 30688651

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194208 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 24.01 KDa
Source organism: Drosophila melanogaster
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9VAR6 (Residues: 35-238; Coverage: 52%)
Gene names: 14521, CG14521, CT34248, DIP-gamma, Dmel\CG14521, Dmel_CG14521, anon-WO0140519.196
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 29.33Å b: 43.44Å c: 86.14Å
α: 90° β: 90.46° γ: 90°
R-values:
R R work R free
0.206 0.204 0.235
Expression system: Trichoplusia ni

Quick links

Citations

5 review citations

Adhesion Protein Structure, Molecular Affinities, and Principles of Cell-Cell Recognition.
Honig et al. (2020)
4 more

1 mention without citation

Antibody recognition of cell surface-associated NS1 triggers Fc-gamma receptor-mediated phagocytosis and clearance of West Nile Virus-infected cells.
Chung et al. (2007)