› 6nut

Electron Microscopy
3.1Å resolution

Ebola virus nucleoprotein - RNA complex

Released:
DOI: 10.2210/pdb6nut/pdb
PDB entry 6nut coloured by chain, front view.
PDB entry 6nut coloured by chain, side view.
PDB entry 6nut coloured by chain, top view.
Source organisms:
Primary publication:
Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Kirchdoerfer RN, Saphire EO, Ward AB
Acta Crystallogr F Struct Biol Commun 75 340-347 (2019)
PMID: 31045563
Related structures: EMD-0522

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 100-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148344 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Nucleoprotein Chain: A
Molecule details ›
Chain: A
Length: 450 amino acids
Theoretical weight: 50.27 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Homo sapiens
UniProt:
  • Canonical: P18272 (Residues: 1-450; Coverage: 61%)
Gene name: NP
Sequence domains: Ebola nucleoprotein
RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3') Chain: D
Molecule details ›
Chain: D
Length: 6 nucleotides
Theoretical weight: 1.93 KDa
Source organism: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-0522
Expression system: Homo sapiens

Quick links

Citations

5 review citations

Viral RNA structure analysis using DMS-MaPseq.
Tomezsko et al. (2020)
4 more

1 mention without citation

Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Kirchdoerfer et al. (2019)