› 6oas

Electron Microscopy
3Å resolution

Structure of canine parvovirus in complex with transferrin receptor type-1

Released:
DOI: 10.2210/pdb6oas/pdb
PDB entry 6oas coloured by chain, front view.
PDB entry 6oas coloured by chain, side view.
PDB entry 6oas coloured by chain, top view.
Source organism: Canine parvovirus 2
Primary publication:
Transferrin receptor binds virus capsid with dynamic motion.
Lee H, Callaway HM, Cifuente JO, Bator CM, Parrish CR, Hafenstein SL
Proc Natl Acad Sci U S A 116 20462-20471 (2019)
PMID: 31548398
Related structures: EMD-20001

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171264 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chain: 1
Molecule details ›
Chain: 1
Length: 548 amino acids
Theoretical weight: 61.56 KDa
Source organism: Canine parvovirus 2
UniProt:
  • Canonical: Q11213 (Residues: 180-727; Coverage: 75%)
Sequence domains: Parvovirus coat protein VP2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-20001

Quick links

Citations

2 review citations

Host receptors: the key to establishing cells with broad viral tropism for vaccine production.
Dai et al. (2020)
1 more

2 mentions without citation

Transferrin receptor binds virus capsid with dynamic motion.
Lee et al. (2019)
1 more