› 6oeg

Electron Microscopy
3.8Å resolution

Structure of CagX from a cryo-EM reconstruction of a T4SS

Released:
DOI: 10.2210/pdb6oeg/pdb
PDB entry 6oeg coloured by chain, front view.
PDB entry 6oeg coloured by chain, side view.
PDB entry 6oeg coloured by chain, top view.
Source organism: Helicobacter pylori
Primary publication:
Structure of the Helicobacter pylori Cag type IV secretion system.
Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD
Elife 8 (2019)
PMID: 31210639
Related structures: EMD-20020

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetradecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104270 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type IV secretion system apparatus protein CagX Chains: N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a
Molecule details ›
Chains: N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a
Length: 522 amino acids
Theoretical weight: 60.72 KDa
Source organism: Helicobacter pylori
UniProt:
  • Canonical: A0A2J9KJM4 (Residues: 1-522; Coverage: 100%)
Gene names: C2840_02745, cagX
Sequence domains: Conjugal transfer protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-20020

Quick links

Citations

14 review citations

Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis.
Takahashi-Kanemitsu et al. (2020)
13 more

4 mentions without citation

The Helicobacter pylori Cag Type IV Secretion System.
Cover et al. (2020)
3 more