› 6of9

X-ray diffraction
3Å resolution

Structure of the Chlamydamonas reinhardtii CamKII hub homology domain

Released:
DOI: 10.2210/pdb6of9/pdb
PDB entry 6of9 coloured by chain, front view.
PDB entry 6of9 coloured by chain, side view.
PDB entry 6of9 coloured by chain, top view.
Source organism: Chlamydomonas reinhardtii
Primary publication:
Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+ /calmodulin-dependent protein kinase II.
McSpadden ED, Xia Z, Chi CC, Susa AC, Shah NH, Gee CL, Williams ER, Kuriyan J
Protein Sci 28 1071-1082 (2019)
PMID: 30942928

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 134 amino acids
Theoretical weight: 14.8 KDa
Source organism: Chlamydomonas reinhardtii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A2K3DJN8 (Residues: 45-178; Coverage: 75%)
Gene name: CHLRE_07g327350v5
Sequence domains: Calcium/calmodulin dependent protein kinase II association domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P41212
Unit cell:
a: 126.464Å b: 126.464Å c: 372.436Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.221 0.251
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Structural Insights into the Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII).
Bhattacharyya et al. (2020)
6 other articles

1 mention without citation

Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+ /calmodulin-dependent protein kinase II.
McSpadden et al. (2019)