PDB 6oli structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate

Biochemical function:

structural constituent of ribosome

Biological process:

translation

Cellular component:

ribosome

Sequence domains:

258 more domains

Structure analysis Details

Assembly composition:

hetero 83-mer (preferred)

PDBe Complex ID:

PDB-CPX-140317 (preferred)

Entry contents:

76 distinct polypeptide molecules
7 distinct RNA molecules

Macromolecules (83 distinct):

Small ribosomal subunit protein uS2 Chain: SA

Molecule details ›

Chain: SA
Length: 221 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P08865 (Residues: 3-223; Coverage: 75%)

Gene names: LAMBR, LAMR1, RPSA
Sequence domains: Ribosomal protein S2

Small ribosomal subunit protein eS1 Chain: SB

Molecule details ›

Chain: SB
Length: 214 amino acids
Theoretical weight: 24.89 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61247 (Residues: 21-234; Coverage: 81%)

Gene names: FTE1, MFTL, RPS3A
Sequence domains: Ribosomal S3Ae family

Small ribosomal subunit protein uS3 Chain: SD

Molecule details ›

Chain: SD
Length: 226 amino acids
Theoretical weight: 25.04 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P23396 (Residues: 2-227; Coverage: 93%)

Gene names: OK/SW-cl.26, RPS3
Sequence domains:

Small ribosomal subunit protein eS4, X isoform Chain: SE

Molecule details ›

Chain: SE
Length: 259 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62701 (Residues: 2-260; Coverage: 99%)

Gene names: CCG2, RPS4, RPS4X, SCAR
Sequence domains:

Small ribosomal subunit protein uS7 Chain: SF

Molecule details ›

Chain: SF
Length: 189 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46782 (Residues: 16-204; Coverage: 93%)

Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e

Small ribosomal subunit protein eS7 Chain: SH

Molecule details ›

Chain: SH
Length: 189 amino acids
Theoretical weight: 21.6 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62081 (Residues: 5-193; Coverage: 97%)

Gene name: RPS7
Sequence domains: Ribosomal protein S7e

Small ribosomal subunit protein eS8 Chain: SI

Molecule details ›

Chain: SI
Length: 204 amino acids
Theoretical weight: 23.82 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62241 (Residues: 2-205; Coverage: 98%)

Gene names: OK/SW-cl.83, RPS8
Sequence domains: Ribosomal protein S8e

Small ribosomal subunit protein eS10 Chain: SK

Molecule details ›

Chain: SK
Length: 98 amino acids
Theoretical weight: 11.77 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46783 (Residues: 1-98; Coverage: 59%)

Gene name: RPS10
Sequence domains: Plectin/S10 domain

Small ribosomal subunit protein uS17 Chain: SL

Molecule details ›

Chain: SL
Length: 153 amino acids
Theoretical weight: 17.79 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62280 (Residues: 2-154; Coverage: 97%)

Gene name: RPS11
Sequence domains:

Small ribosomal subunit protein uS19 Chain: SP

Molecule details ›

Chain: SP
Length: 127 amino acids
Theoretical weight: 14.93 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62841 (Residues: 10-136; Coverage: 88%)

Gene names: RIG, RPS15
Sequence domains: Ribosomal protein S19

Small ribosomal subunit protein uS9 Chain: SQ

Molecule details ›

Chain: SQ
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62249 (Residues: 1-146; Coverage: 100%)

Gene name: RPS16
Sequence domains: Ribosomal protein S9/S16

Small ribosomal subunit protein eS17 Chain: SR

Molecule details ›

Chain: SR
Length: 134 amino acids
Theoretical weight: 15.45 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P08708 (Residues: 2-135; Coverage: 99%)

Gene names: RPS17, RPS17L
Sequence domains: Ribosomal S17

Small ribosomal subunit protein uS13 Chain: SS

Molecule details ›

Chain: SS
Length: 145 amino acids
Theoretical weight: 17.03 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62269 (Residues: 1-145; Coverage: 95%)

Gene names: D6S218E, RPS18
Sequence domains: Ribosomal protein S13/S18

Small ribosomal subunit protein eS19 Chain: ST

Molecule details ›

Chain: ST
Length: 143 amino acids
Theoretical weight: 15.82 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P39019 (Residues: 2-144; Coverage: 99%)

Gene name: RPS19
Sequence domains: Ribosomal protein S19e

Small ribosomal subunit protein uS10 Chain: SU

Molecule details ›

Chain: SU
Length: 104 amino acids
Theoretical weight: 11.77 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P60866 (Residues: 16-119; Coverage: 87%)

Gene name: RPS20
Sequence domains: Ribosomal protein S10p/S20e

Small ribosomal subunit protein eS21 Chain: SV

Molecule details ›

Chain: SV
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P63220 (Residues: 1-82; Coverage: 99%)

Gene name: RPS21
Sequence domains: Ribosomal protein S21e

Small ribosomal subunit protein uS12 Chain: SX

Molecule details ›

Chain: SX
Length: 141 amino acids
Theoretical weight: 15.63 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62266 (Residues: 2-142; Coverage: 99%)

Gene name: RPS23
Sequence domains: Ribosomal protein S12/S23

Small ribosomal subunit protein eS26 Chain: Sa

Molecule details ›

Chain: Sa
Length: 102 amino acids
Theoretical weight: 11.74 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62854 (Residues: 2-103; Coverage: 89%)

Gene name: RPS26
Sequence domains: Ribosomal protein S26e

Small ribosomal subunit protein eS28 Chain: Sc

Molecule details ›

Chain: Sc
Length: 64 amino acids
Theoretical weight: 7.26 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62857 (Residues: 5-68; Coverage: 93%)

Gene name: RPS28
Sequence domains: Ribosomal protein S28e

Small ribosomal subunit protein uS14 Chain: Sd

Molecule details ›

Chain: Sd
Length: 55 amino acids
Theoretical weight: 6.56 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62273 (Residues: 2-56; Coverage: 98%)

Gene name: RPS29
Sequence domains: Ribosomal protein S14p/S29e

Small ribosomal subunit protein RACK1 Chain: Sg

Molecule details ›

Chain: Sg
Length: 312 amino acids
Theoretical weight: 34.57 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P63244 (Residues: 3-314; Coverage: 98%)

Gene names: GNB2L1, HLC7, PIG21, RACK1
Sequence domains: WD domain, G-beta repeat

Small ribosomal subunit protein uS5 Chain: SC

Molecule details ›

Chain: SC
Length: 220 amino acids
Theoretical weight: 24.33 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P15880 (Residues: 59-278; Coverage: 75%)

Gene names: RPS2, RPS4
Sequence domains:

Small ribosomal subunit protein eS6 Chain: SG

Molecule details ›

Chain: SG
Length: 237 amino acids
Theoretical weight: 27.47 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62753 (Residues: 1-237; Coverage: 95%)

Gene names: OK/SW-cl.2, RPS6
Sequence domains: Ribosomal protein S6e

Small ribosomal subunit protein uS4 Chain: SJ

Molecule details ›

Chain: SJ
Length: 185 amino acids
Theoretical weight: 21.65 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46781 (Residues: 2-186; Coverage: 95%)

Gene name: RPS9
Sequence domains:

Small ribosomal subunit protein eS12 Chain: SM

Molecule details ›

Chain: SM
Length: 118 amino acids
Theoretical weight: 13.22 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P25398 (Residues: 15-132; Coverage: 89%)

Gene name: RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

Small ribosomal subunit protein uS15 Chain: SN

Molecule details ›

Chain: SN
Length: 150 amino acids
Theoretical weight: 17.13 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62277 (Residues: 2-151; Coverage: 99%)

Gene name: RPS13
Sequence domains:

Small ribosomal subunit protein uS11 Chain: SO

Molecule details ›

Chain: SO
Length: 137 amino acids
Theoretical weight: 14.66 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62263 (Residues: 15-151; Coverage: 91%)

Gene names: PRO2640, RPS14
Sequence domains: Ribosomal protein S11

Small ribosomal subunit protein uS8 Chain: SW

Molecule details ›

Chain: SW
Length: 129 amino acids
Theoretical weight: 14.73 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62244 (Residues: 2-130; Coverage: 99%)

Gene names: OK/SW-cl.82, RPS15A
Sequence domains: Ribosomal protein S8

Small ribosomal subunit protein eS24 Chain: SY

Molecule details ›

Chain: SY
Length: 131 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62847 (Residues: 2-132; Coverage: 99%)

Gene name: RPS24
Sequence domains: Ribosomal protein S24e

Small ribosomal subunit protein eS25 Chain: SZ

Molecule details ›

Chain: SZ
Length: 73 amino acids
Theoretical weight: 8.25 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62851 (Residues: 43-115; Coverage: 58%)

Gene name: RPS25
Sequence domains: S25 ribosomal protein

Small ribosomal subunit protein eS27 Chain: Sb

Molecule details ›

Chain: Sb
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P42677 (Residues: 2-83; Coverage: 98%)

Gene names: MPS1, RPS27
Sequence domains: Ribosomal protein S27

Small ribosomal subunit protein eS30 Chain: Se

Molecule details ›

Chain: Se
Length: 57 amino acids
Theoretical weight: 6.45 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62861 (Residues: 76-132; Coverage: 43%)

Gene name: FAU
Sequence domains: Ribosomal protein S30

Small ribosomal subunit protein eS31 Chain: Sf

Molecule details ›

Chain: Sf
Length: 67 amino acids
Theoretical weight: 7.88 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62979 (Residues: 85-151; Coverage: 43%)

Gene names: RPS27A, UBA80, UBCEP1
Sequence domains: Ribosomal protein S27a

Large ribosomal subunit protein uL2 Chain: A

Molecule details ›

Chain: A
Length: 252 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62917 (Residues: 2-253; Coverage: 98%)

Gene name: RPL8
Sequence domains:

Large ribosomal subunit protein uL3 Chain: B

Molecule details ›

Chain: B
Length: 397 amino acids
Theoretical weight: 45.56 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P39023 (Residues: 2-398; Coverage: 99%)

Gene names: OK/SW-cl.32, RPL3
Sequence domains: Ribosomal protein L3

Large ribosomal subunit protein uL4 Chain: C

Molecule details ›

Chain: C
Length: 363 amino acids
Theoretical weight: 41.17 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P36578 (Residues: 3-365; Coverage: 85%)

Gene names: RPL1, RPL4
Sequence domains:

Large ribosomal subunit protein uL18 Chain: F

Molecule details ›

Chain: F
Length: 294 amino acids
Theoretical weight: 34.09 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46777 (Residues: 4-297; Coverage: 99%)

Gene names: MSTP030, RPL5
Sequence domains:

Large ribosomal subunit protein eL6 Chain: G

Molecule details ›

Chain: G
Length: 247 amino acids
Theoretical weight: 28.38 KDa
Source organism: Homo sapiens
UniProt:

Canonical: Q02878 (Residues: 42-288; Coverage: 86%)

Gene names: RPL6, TXREB1
Sequence domains:

Large ribosomal subunit protein uL30 Chain: H

Molecule details ›

Chain: H
Length: 225 amino acids
Theoretical weight: 26.59 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P18124 (Residues: 24-248; Coverage: 91%)

Gene name: RPL7
Sequence domains:

Large ribosomal subunit protein eL8 Chain: I

Molecule details ›

Chain: I
Length: 234 amino acids
Theoretical weight: 26.72 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62424 (Residues: 29-262; Coverage: 88%)

Gene names: RPL7A, SURF-3, SURF3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

Large ribosomal subunit protein uL6 Chain: J

Molecule details ›

Chain: J
Length: 191 amino acids
Theoretical weight: 21.77 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P32969 (Residues: 1-191; Coverage: 100%)

Gene names: OK/SW-cl.103, RPL9, RPL9P7, RPL9P8, RPL9P9
Sequence domains: Ribosomal protein L6

Large ribosomal subunit protein uL16 Chain: K

Molecule details ›

Chain: K
Length: 211 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P27635 (Residues: 3-213; Coverage: 99%)

Gene names: DXS648E, QM, RPL10
Sequence domains: Ribosomal protein L16p/L10e

Large ribosomal subunit protein uL5 Chain: L

Molecule details ›

Chain: L
Length: 169 amino acids
Theoretical weight: 19.27 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62913 (Residues: 9-177; Coverage: 95%)

Gene name: RPL11
Sequence domains:

Large ribosomal subunit protein eL13 Chain: M

Molecule details ›

Chain: M
Length: 205 amino acids
Theoretical weight: 23.57 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P26373 (Residues: 2-206; Coverage: 97%)

Gene names: BBC1, OK/SW-cl.46, RPL13
Sequence domains: Ribosomal protein L13e

Large ribosomal subunit protein eL14 Chain: N

Molecule details ›

Chain: N
Length: 139 amino acids
Theoretical weight: 16.22 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P50914 (Residues: 2-140; Coverage: 65%)

Gene name: RPL14
Sequence domains: Ribosomal protein L14

Large ribosomal subunit protein eL15 Chain: O

Molecule details ›

Chain: O
Length: 203 amino acids
Theoretical weight: 24.08 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61313 (Residues: 2-204; Coverage: 100%)

Gene names: EC45, RPL15, TCBAP0781
Sequence domains: Ribosomal L15

Large ribosomal subunit protein uL13 Chain: P

Molecule details ›

Chain: P
Length: 195 amino acids
Theoretical weight: 22.82 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P40429 (Residues: 5-199; Coverage: 96%)

Gene name: RPL13A
Sequence domains: Ribosomal protein L13

Large ribosomal subunit protein uL22 Chain: Q

Molecule details ›

Chain: Q
Length: 153 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P18621 (Residues: 2-154; Coverage: 83%)

Gene name: RPL17
Sequence domains: Ribosomal protein L22p/L17e

Large ribosomal subunit protein eL18 Chain: R

Molecule details ›

Chain: R
Length: 187 amino acids
Theoretical weight: 21.56 KDa
Source organism: Homo sapiens
UniProt:

Canonical: Q07020 (Residues: 2-188; Coverage: 100%)

Gene name: RPL18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e

Large ribosomal subunit protein eL19 Chain: S

Molecule details ›

Chain: S
Length: 181 amino acids
Theoretical weight: 21.74 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P84098 (Residues: 2-182; Coverage: 92%)

Gene name: RPL19
Sequence domains: Ribosomal protein L19e

Large ribosomal subunit protein eL20 Chain: T

Molecule details ›

Chain: T
Length: 175 amino acids
Theoretical weight: 20.66 KDa
Source organism: Homo sapiens
UniProt:

Canonical: Q02543 (Residues: 1-175; Coverage: 99%)

Gene name: RPL18A
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A

Large ribosomal subunit protein eL21 Chain: U

Molecule details ›

Chain: U
Length: 157 amino acids
Theoretical weight: 18.28 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46778 (Residues: 2-158; Coverage: 98%)

Gene name: RPL21
Sequence domains: Ribosomal protein L21e

Large ribosomal subunit protein eL22 Chain: V

Molecule details ›

Chain: V
Length: 99 amino acids
Theoretical weight: 11.48 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P35268 (Residues: 18-116; Coverage: 77%)

Gene name: RPL22
Sequence domains: Ribosomal L22e protein family

Large ribosomal subunit protein uL14 Chain: W

Molecule details ›

Chain: W
Length: 129 amino acids
Theoretical weight: 13.83 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62829 (Residues: 12-140; Coverage: 92%)

Gene name: RPL23
Sequence domains: Ribosomal protein L14p/L23e

Large ribosomal subunit protein eL24 Chain: X

Molecule details ›

Chain: X
Length: 61 amino acids
Theoretical weight: 7.25 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P83731 (Residues: 2-62; Coverage: 39%)

Gene name: RPL24
Sequence domains: Ribosomal protein L24e

Large ribosomal subunit protein uL23 Chain: Y

Molecule details ›

Chain: Y
Length: 117 amino acids
Theoretical weight: 13.61 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62750 (Residues: 39-155; Coverage: 75%)

Gene name: RPL23A
Sequence domains:

Large ribosomal subunit protein uL24 Chain: Z

Molecule details ›

Chain: Z
Length: 134 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61254 (Residues: 1-134; Coverage: 92%)

Gene name: RPL26
Sequence domains:

Large ribosomal subunit protein eL27 Chain: a

Molecule details ›

Chain: a
Length: 134 amino acids
Theoretical weight: 15.65 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61353 (Residues: 3-136; Coverage: 99%)

Gene name: RPL27
Sequence domains:

Large ribosomal subunit protein uL15 Chain: b

Molecule details ›

Chain: b
Length: 147 amino acids
Theoretical weight: 16.47 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46776 (Residues: 2-148; Coverage: 99%)

Gene name: RPL27A
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A

Large ribosomal subunit protein eL29 Chain: c

Molecule details ›

Chain: c
Length: 121 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P47914 (Residues: 2-122; Coverage: 76%)

Gene name: RPL29
Sequence domains: Ribosomal L29e protein family

Large ribosomal subunit protein eL30 Chain: d

Molecule details ›

Chain: d
Length: 103 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62888 (Residues: 7-109; Coverage: 90%)

Gene name: RPL30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

Large ribosomal subunit protein eL31 Chain: e

Molecule details ›

Chain: e
Length: 106 amino acids
Theoretical weight: 12.51 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62899 (Residues: 18-123; Coverage: 85%)

Gene name: RPL31
Sequence domains: Ribosomal protein L31e

Large ribosomal subunit protein eL32 Chain: f

Molecule details ›

Chain: f
Length: 129 amino acids
Theoretical weight: 15.18 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62910 (Residues: 2-130; Coverage: 96%)

Gene names: PP9932, RPL32
Sequence domains: Ribosomal protein L32

Large ribosomal subunit protein eL33 Chain: g

Molecule details ›

Chain: g
Length: 109 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P18077 (Residues: 2-110; Coverage: 99%)

Gene names: GIG33, RPL35A
Sequence domains: Ribosomal protein L35Ae

Large ribosomal subunit protein eL34 Chain: h

Molecule details ›

Chain: h
Length: 114 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P49207 (Residues: 2-115; Coverage: 97%)

Gene name: RPL34
Sequence domains: Ribosomal protein L34e

Large ribosomal subunit protein uL29 Chain: i

Molecule details ›

Chain: i
Length: 122 amino acids
Theoretical weight: 14.46 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P42766 (Residues: 2-123; Coverage: 99%)

Gene name: RPL35
Sequence domains: Ribosomal L29 protein

Large ribosomal subunit protein eL36 Chain: j

Molecule details ›

Chain: j
Length: 97 amino acids
Theoretical weight: 11.37 KDa
Source organism: Homo sapiens
UniProt:

Canonical: Q9Y3U8 (Residues: 5-101; Coverage: 92%)

Gene name: RPL36
Sequence domains: Ribosomal protein L36e

Large ribosomal subunit protein eL37 Chain: k

Molecule details ›

Chain: k
Length: 84 amino acids
Theoretical weight: 9.86 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61927 (Residues: 2-85; Coverage: 87%)

Gene name: RPL37
Sequence domains: Ribosomal protein L37e

Large ribosomal subunit protein eL38 Chain: l

Molecule details ›

Chain: l
Length: 69 amino acids
Theoretical weight: 8.11 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P63173 (Residues: 2-70; Coverage: 99%)

Gene name: RPL38
Sequence domains: Ribosomal L38e protein family

Large ribosomal subunit protein eL39 Chain: m

Molecule details ›

Chain: m
Length: 50 amino acids
Theoretical weight: 6.3 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62891 (Residues: 2-51; Coverage: 98%)

Gene name: RPL39
Sequence domains: Ribosomal L39 protein

Large ribosomal subunit protein eL40 Chain: n

Molecule details ›

Chain: n
Length: 50 amino acids
Theoretical weight: 5.96 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62987 (Residues: 78-127; Coverage: 39%)

Gene names: UBA52, UBCEP2
Sequence domains: Ribosomal L40e family

Small ribosomal subunit protein eS32 Chain: o

Molecule details ›

Chain: o
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P62945 (Residues: 1-25; Coverage: 100%)

Gene name: RPL41
Sequence domains: Ribosomal protein L41

Large ribosomal subunit protein eL42 Chain: p

Molecule details ›

Chain: p
Length: 105 amino acids
Theoretical weight: 12.35 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P83881 (Residues: 2-106; Coverage: 99%)

Gene names: GIG15, MIG6, RPL36A, RPL44
Sequence domains: Ribosomal protein L44

Large ribosomal subunit protein eL43 Chain: q

Molecule details ›

Chain: q
Length: 91 amino acids
Theoretical weight: 10.17 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61513 (Residues: 2-92; Coverage: 99%)

Gene name: RPL37A
Sequence domains: Ribosomal L37ae protein family

Large ribosomal subunit protein eL28 Chain: r

Molecule details ›

Chain: r
Length: 122 amino acids
Theoretical weight: 13.99 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46779 (Residues: 2-123; Coverage: 89%)

Gene name: RPL28
Sequence domains: Ribosomal L28e protein family

Nascent chain Chain: y

Molecule details ›

Chain: y
Length: 36 amino acids
Theoretical weight: 3.08 KDa
Source organism: Homo sapiens

18S Ribosomal RNA Chain: S2

Molecule details ›

Chain: S2
Length: 1714 nucleotides
Theoretical weight: 553.51 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA

5.8S ribosomal RNA Chain: D

Molecule details ›

Chain: D
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Sequence domains: 5.8S ribosomal RNA

5S ribosomal RNA Chain: E

Molecule details ›

Chain: E
Length: 121 nucleotides
Theoretical weight: 39 KDa
Sequence domains: 5S ribosomal RNA

28S ribosomal RNA Chain: t

Molecule details ›

Chain: t
Length: 3607 nucleotides
Theoretical weight: 1168.72 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA

tRNA Chain: u

Molecule details ›

Chain: u
Length: 76 nucleotides
Theoretical weight: 24.41 KDa
Sequence domains: tRNA

tRNA Chain: v

Molecule details ›

Chain: v
Length: 76 nucleotides
Theoretical weight: 24.44 KDa
Sequence domains: tRNA

Messenger RNA Chain: w

Molecule details ›

Chain: w
Length: 10 nucleotides
Theoretical weight: 3.19 KDa

Ligands and Environments

3 bound ligands:

13 modified residues:

Experiments and Validation Details

Resolution: 3.5Å

Relevant EMDB volumes: EMD-0526

Protein Data Bank in Europe

Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)

Function and Biology Details

Structure analysis Details

Ligands and Environments

Experiments and Validation Details

Quick links

Citations

10 review citations

2 mentions without citation

PDBe › 6oli

Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)

Function and Biology Details

Structure analysis Details

Ligands and Environments

Experiments and Validation Details

Quick links

Citations

10 review citations

2 mentions without citation