› 6ont

X-ray diffraction
1.8Å resolution

Structure of the Francisella response regulator 1452 receiver domain

Released:
DOI: 10.2210/pdb6ont/pdb
Model geometry
Data not analysed
Fit model/data
Data not analysed
PDB entry 6ont coloured by chain, front view.
PDB entry 6ont coloured by chain, side view.
PDB entry 6ont coloured by chain, top view.
Source organism: Francisella tularensis subsp. novicida U112
Primary publication:
Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production.
Dean SN, Milton ME, Cavanagh J, van Hoek ML
OpenAccess logo Front Cell Infect Microbiol 10 82 (2020)
PMID: 32232010

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106197 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Two-component response regulator Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 14.94 KDa
Source organism: Francisella tularensis subsp. novicida U112
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0Q7V5 (Residues: 1-129; Coverage: 56%)
Gene name: FTN_1452
Sequence domains: Response regulator receiver domain

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand NA 2 x NA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: I4132
Unit cell:
a: 128.726Å b: 128.726Å c: 128.726Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.202
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Genetic Determinants of Antibiotic Resistance in Francisella.
Kassinger et al. (2021)
2 more

2 mentions without citation

Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production.
Dean et al. (2020)
1 more