6osy

Electron Microscopy
4.3Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 24-mer (preferred)
PDBe Complex ID:
PDB-CPX-212156 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (15 distinct):
Envelope glycoprotein gp160 Chains: 2, B, K
Molecule details ›
Chains: 2, B, K
Length: 480 amino acids
Theoretical weight: 53.99 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-508; Coverage: 56%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
PGT122 Heavy Chains: 5, C, M
Molecule details ›
Chains: 5, C, M
Length: 235 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT122 Light Chains: 6, D, N
Molecule details ›
Chains: 6, D, N
Length: 213 amino acids
Theoretical weight: 22.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VRC03 Light Chains: 7, E, O
Molecule details ›
Chains: 7, E, O
Length: 209 amino acids
Theoretical weight: 23.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VRC03 Heavy Chains: 8, F, P
Molecule details ›
Chains: 8, F, P
Length: 233 amino acids
Theoretical weight: 25.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Transmembrane protein gp41 Chains: A, G, Q
Molecule details ›
Chains: A, G, Q
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
0PV-a.01 Heavy Chains: H, I, R
Molecule details ›
Chains: H, I, R
Length: 235 amino acids
Theoretical weight: 25.41 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
0PV-a.01 Light Chains: J, L, S
Molecule details ›
Chains: J, L, S
Length: 213 amino acids
Theoretical weight: 23.41 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-20189
Expression system: Homo sapiens