6ot1

Electron Microscopy
3.5Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 24-mer (preferred)
PDBe Complex ID:
PDB-CPX-212157 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (13 distinct):
Transmembrane protein gp41 Chains: B, D, O
Molecule details ›
Chains: B, D, O
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
Envelope glycoprotein gp160 Chains: E, G, P
Molecule details ›
Chains: E, G, P
Length: 480 amino acids
Theoretical weight: 53.99 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-508; Coverage: 56%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
0PV-b.01 heavy Chains: A, H, M
Molecule details ›
Chains: A, H, M
Length: 230 amino acids
Theoretical weight: 24.43 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
0PV-b.01 light Chains: C, L, N
Molecule details ›
Chains: C, L, N
Length: 219 amino acids
Theoretical weight: 23.84 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
PGT122 heavy Chains: F, Q, m
Molecule details ›
Chains: F, Q, m
Length: 235 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT122 light Chains: I, R, n
Molecule details ›
Chains: I, R, n
Length: 213 amino acids
Theoretical weight: 22.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VRC03 heavy Chains: J, S, q
Molecule details ›
Chains: J, S, q
Length: 233 amino acids
Theoretical weight: 25.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VRC03 light Chains: K, T, r
Molecule details ›
Chains: K, T, r
Length: 209 amino acids
Theoretical weight: 23.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-20191
Expression system: Homo sapiens