6ozc

Electron Microscopy
3.79Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
PDBe Complex ID:
PDB-CPX-212159 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (11 distinct):
Envelope glycoprotein gp160 Chains: A, E, F
Molecule details ›
Chains: A, E, F
Length: 475 amino acids
Theoretical weight: 53.12 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-504; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chains: B, G, I
Molecule details ›
Chains: B, G, I
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
2G12 Fab light chain Chains: D, L, M, N, Q, R
Molecule details ›
Chains: D, L, M, N, Q, R
Length: 213 amino acids
Theoretical weight: 23.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
2G12 Fab Heavy chain Chains: C, H, J, K, O, P
Molecule details ›
Chains: C, H, J, K, O, P
Length: 224 amino acids
Theoretical weight: 23.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.79Å
Relevant EMDB volumes: EMD-20224
Expression system: Homo sapiens