› 6p0q

X-ray diffraction
1.72Å resolution

Crystal Structure of Ubiquitin-like Domain of Human WDR12

Released:
DOI: 10.2210/pdb6p0q/pdb
PDB entry 6p0q coloured by chain, front view.
PDB entry 6p0q coloured by chain, side view.
PDB entry 6p0q coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Halabelian L, Dong A, Zeng H, Li Y, Bountra C, Edwards AM, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome biogenesis protein WDR12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 94 amino acids
Theoretical weight: 11.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9GZL7 (Residues: 1-87; Coverage: 21%)
Gene name: WDR12
Sequence domains: NLE (NUC135) domain

Ligands and Environments

1 bound ligand:
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 41.197Å b: 50.91Å c: 47.811Å
α: 90° β: 94.11° γ: 90°
R-values:
R R work R free
0.177 0.174 0.223
Expression system: Escherichia coli BL21(DE3)

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