6p3q

X-ray diffraction
2.8Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calpain-5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 359 amino acids
Theoretical weight: 41.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O15484 (Residues: 1-343; Coverage: 54%)
Gene names: CAPN5, NCL3
Sequence domains: Calpain family cysteine protease

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 84.038Å b: 51.576Å c: 110.635Å
α: 90° β: 110.425° γ: 90°
R-values:
R R work R free
0.23 0.227 0.285
Expression system: Escherichia coli BL21