› 6p4l

Electron Microscopy
3.1Å resolution

Bile salts alter the mouse norovirus capsid conformation; possible implications for cell attachment and immune evasion.

Released:
DOI: 10.2210/pdb6p4l/pdb
PDB entry 6p4l coloured by chain, front view.
PDB entry 6p4l coloured by chain, side view.
PDB entry 6p4l coloured by chain, top view.
Source organism: Murine norovirus 1
Primary publication:
Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
Sherman MB, Williams AN, Smith HQ, Nelson C, Wilen CB, Fremont DH, Virgin HW, Smith TJ
J Virol 93 (2019)
PMID: 31341042
Related structures: EMD-20252

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo 180-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174090 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ORF2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 541 amino acids
Theoretical weight: 58.7 KDa
Source organism: Murine norovirus 1
Expression system: Murine norovirus 1
UniProt:
  • Canonical: Q2V8W4 (Residues: 1-541; Coverage: 100%)
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-20252
Expression system: Murine norovirus 1

Quick links

Citations

10 review citations

Virus interactions with bacteria: Partners in the infectious dance.
Neu et al. (2020)
9 more

2 mentions without citation

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
Sherman et al. (2019)
1 more