› 6p7t

X-ray diffraction
2.5Å resolution

Crystal structure of apo ToxT K231A from Vibrio cholerae strain SCE256

Released:
DOI: 10.2210/pdb6p7t/pdb
PDB entry 6p7t coloured by chain, front view.
PDB entry 6p7t coloured by chain, side view.
PDB entry 6p7t coloured by chain, top view.
Source organism: Vibrio cholerae
Primary publication:
Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile.
Cruite JT, Kovacikova G, Clark KA, Woodbrey AK, Skorupski K, Kull FJ
Commun Biol 2 440 (2019)
PMID: 31815195

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190257 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH araC/xylS-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 277 amino acids
Theoretical weight: 32.16 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9F5Q9 (Residues: 1-277; Coverage: 100%)
Gene name: tcpN
Sequence domains: Helix-turn-helix domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS-II BEAMLINE 17-ID-2
Spacegroup: C2
Unit cell:
a: 79.8Å b: 45.5Å c: 77Å
α: 90° β: 97.7° γ: 90°
R-values:
R R work R free
0.25 0.246 0.287
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae.
Ramamurthy et al. (2020)
4 more

1 mention without citation

Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile.
Cruite et al. (2019)