› 6p8p

X-ray diffraction
1.64Å resolution

Structure of P. aeruginosa ATCC27853 HORMA1

Released:
DOI: 10.2210/pdb6p8p/pdb
PDB entry 6p8p coloured by chain, front view.
PDB entry 6p8p coloured by chain, side view.
PDB entry 6p8p coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye Q, Lau RK, Mathews IT, Birkholz EA, Watrous JD, Azimi CS, Pogliano J, Jain M, Corbett KD
Mol Cell 77 709-722.e7 (2020)
PMID: 31932165

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145116 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD-NTase-associated protein 8 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 156 amino acids
Theoretical weight: 16.72 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTF5 (Residues: 1-156; Coverage: 100%)
Gene names: A4W92_29525, HORMA3, cap8

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P4
Unit cell:
a: 97.525Å b: 97.525Å c: 60.134Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.198
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Bacterial origins of human cell-autonomous innate immune mechanisms.
Wein et al. (2022)
18 more

1 mention without citation

HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye et al. (2020)