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› 6pa0

X-ray diffraction
2.05Å resolution

Structure of the G77A mutant in Sodium Chloride

Released:
DOI: 10.2210/pdb6pa0/pdb
Model geometry
Fit model/data
PDB entry 6pa0 coloured by chain, front view.
PDB entry 6pa0 coloured by chain, side view.
PDB entry 6pa0 coloured by chain, top view.
Source organisms:
Primary publication:
Structure, function, and ion-binding properties of a K+ channel stabilized in the 2,4-ion-bound configuration.
Tilegenova C, Cortes DM, Jahovic N, Hardy E, Hariharan P, Guan L, Cuello LG
Proc Natl Acad Sci U S A 116 16829-16834 (2019)
PMID: 31387976

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209491 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Antibody HEAVY fragment Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 23.41 KDa
Source organism: Mus musculus
Antibody LIGHT fragment Chain: B
Molecule details ›
Chain: B
Length: 212 amino acids
Theoretical weight: 23.44 KDa
Source organism: Mus musculus
pH-gated potassium channel KcsA Chain: C

Ligands and Environments

3 bound ligands:
Ligand F09 1 x F09
Ligand DGA 1 x DGA
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: I4
Unit cell:
a: 155.018Å b: 155.018Å c: 76.102Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.233
Expression system: Escherichia coli

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Citations

1 review citation

The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions.
Wu et al. (2021)
12 other articles

1 mention without citation

Structure, function, and ion-binding properties of a K+ channel stabilized in the 2,4-ion-bound configuration.
Tilegenova et al. (2019)