6pbg

X-ray diffraction
1.72Å resolution

Crystal structure of WD-repeat domain of human coatomer subunit Alpha (COPA)

Released:
Source organism: Homo sapiens
Entry authors: Halabelian L, Zeng H, Dong A, Loppnau P, Seitova A, Hutchinson A, Bountra C, Edwards AM, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156839 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coatomer subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 37.07 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P53621 (Residues: 1-320; Coverage: 26%)
Gene name: COPA
Sequence domains: WD domain, G-beta repeat

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 34.633Å b: 85.452Å c: 47.913Å
α: 90° β: 107.04° γ: 90°
R-values:
R R work R free
0.173 0.171 0.218
Expression system: Spodoptera frugiperda