Function and Biology Details
Reactions catalysed:
UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L-threo-pentapyranos-4-ulose + CO(2) + NADH
10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinose
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- NAD-dependent epimerase/dehydratase
- Bifunctional polymyxin resistance protein ArnA-like, extended (e) SDRs
- NAD(P)-binding domain superfamily
- Formyl transferase-like, C-terminal domain superfamily
- Formyl transferase, C-terminal
- Formyl transferase, N-terminal
- Formyl transferase, N-terminal domain superfamily
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
Bifunctional polymyxin resistance protein ArnA (preferred)
PDBe Complex ID:
PDB-CPX-160164 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bifunctional polymyxin resistance protein ArnA
Molecule details ›
Bifunctional polymyxin resistance protein ArnA
Molecule details ›
Chains: G, H, I, J, K, L
Length: 345 amino acids
Theoretical weight: 40.06 KDa
Source organism: Escherichia coli DH5[alpha]
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: NAD dependent epimerase/dehydratase family
Length: 345 amino acids
Theoretical weight: 40.06 KDa
Source organism: Escherichia coli DH5[alpha]
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P77398 (Residues: 317-660; Coverage: 52%)
Sequence domains: NAD dependent epimerase/dehydratase family
