Function and Biology Details
Reaction catalysed:
Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein gurken and Rhomboid protease GlpG (preferred)
PDBe Complex ID:
PDB-CPX-140630 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rhomboid protease GlpG
Molecule details ›
Chain: A
Length: 211 amino acids
Theoretical weight: 23.8 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Rhomboid domain
Length: 211 amino acids
Theoretical weight: 23.8 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P09391 (Residues: 87-276; Coverage: 69%)
Sequence domains: Rhomboid domain
Protein gurken
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.52 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
Length: 13 amino acids
Theoretical weight: 1.52 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
- Canonical: P42287 (Residues: 241-253; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
CHESS BEAMLINE F1
Spacegroup:
C2221
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
