Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Beta-lactamase/transpeptidase-like
- Probable peptidoglycan glycosyltransferase RodA/MrdB
- Probable peptidoglycan glycosyltransferase FtsW/RodA
- Penicillin-binding protein, transpeptidase
- Penicillin-binding protein, dimerisation domain
- Penicillin-binding protein, dimerisation domain superfamily
- Cell cycle, FtsW / RodA / SpoVE, conserved site
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-167248 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Peptidoglycan glycosyltransferase RodA
Molecule details ›
Chain: A
Length: 377 amino acids
Theoretical weight: 40.55 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Cell cycle protein
Length: 377 amino acids
Theoretical weight: 40.55 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q5SIX3 (Residues: 2-359; Coverage: 100%)
Sequence domains: Cell cycle protein
Penicillin-binding protein 2/cell division protein FtsI
Molecule details ›
Chain: B
Length: 598 amino acids
Theoretical weight: 65.45 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains:
Length: 598 amino acids
Theoretical weight: 65.45 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical: Q5SJ23 (Residues: 2-575; Coverage: 100%)
Sequence domains:
Ligands and Environments
1 bound ligand:
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 23-ID-D
Spacegroup:
P3221
Expression systems:
- Escherichia coli BL21(DE3)
- Escherichia coli 'BL21-Gold(DE3)pLysS AG'
