6pol

X-ray diffraction
1.8Å resolution

Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-187771 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Roundabout homolog 3 Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 114 amino acids
Theoretical weight: 12.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q96MS0 (Residues: 549-652; Coverage: 8%)
Gene name: ROBO3
Sequence domains: Fibronectin type III domain
Protein kinase C-binding protein NELL1 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 139 amino acids
Theoretical weight: 15.3 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q92832 (Residues: 390-517; Coverage: 16%)
Gene names: NELL1, NRP1
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P3121
Unit cell:
a: 87Å b: 87Å c: 211.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.23 0.267
Expression system: Trichoplusia ni