Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Insulin receptor subunit beta and Insulin (preferred)
PDBe Complex ID:
PDB-CPX-108154 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin receptor
Molecule details ›
Chains: A, C
Length: 1354 amino acids
Theoretical weight: 153.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1354 amino acids
Theoretical weight: 153.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P06213 (Residues: 28-1382; Coverage: 99%)
Sequence domains:
Insulin
Molecule details ›
Chains: D, E, F, G
Length: 74 amino acids
Theoretical weight: 8.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Length: 74 amino acids
Theoretical weight: 8.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: A6XGL2 (Residues: 25-98; Coverage: 100%)
Sequence domains: Insulin/IGF/Relaxin family
