6pz8

Electron Microscopy
4.19Å resolution

MERS S0 trimer in complex with variable domain of antibody G2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-207963 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Spike protein S2' Chains: A, E, I
Molecule details ›
Chains: A, E, I
Length: 472 amino acids
Theoretical weight: 51.3 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: K9N5Q8 (Residues: 752-1223; Coverage: 35%)
Gene names: 3, S
Sequence domains: Coronavirus spike glycoprotein S2
Spike protein S1 Chains: B, F, J
Molecule details ›
Chains: B, F, J
Length: 726 amino acids
Theoretical weight: 80.41 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: K9N5Q8 (Residues: 18-743; Coverage: 54%)
Gene names: 3, S
Sequence domains:
G2 heavy chain Chains: C, D, H
Molecule details ›
Chains: C, D, H
Length: 229 amino acids
Theoretical weight: 24.28 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
G2 light chain Chains: G, K, L
Molecule details ›
Chains: G, K, L
Length: 218 amino acids
Theoretical weight: 23.86 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.19Å
Relevant EMDB volumes: EMD-20527
Expression system: Homo sapiens