Function and Biology Details
Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232190 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Neuraminidase
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.98 KDa
Source organism: Influenza A virus (A/Shanghai/02/2013(H7N9))
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Neuraminidase
Length: 393 amino acids
Theoretical weight: 43.98 KDa
Source organism: Influenza A virus (A/Shanghai/02/2013(H7N9))
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
R4NFR6 (Residues: 76-465; Coverage: 84%)
Sequence domains: Neuraminidase
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 23-ID-D
Spacegroup:
P4212
Expression systems:
- Spodoptera frugiperda
- Cricetulus griseus
