6q06

Electron Microscopy
2.7Å resolution

MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-125457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (7 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1359 amino acids
Theoretical weight: 149.17 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Homo sapiens
UniProt:
  • Canonical: K0BRG7 (Residues: 19-1294; Coverage: 94%)
Gene name: S
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: GAL, SIA
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-20544
Expression system: Homo sapiens