Function and Biology Details
Reaction catalysed:
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Angiostatin and Trypsin inhibitor 1 (preferred)
PDBe Complex ID:
PDB-CPX-133234 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasmin light chain B
Molecule details ›
Chains: A, B
Length: 249 amino acids
Theoretical weight: 27.26 KDa
Source organism: Homo sapiens
Expression system: Komagataella phaffii GS115
UniProt:
Sequence domains: Trypsin
Length: 249 amino acids
Theoretical weight: 27.26 KDa
Source organism: Homo sapiens
Expression system: Komagataella phaffii GS115
UniProt:
- Canonical:
P00747 (Residues: 562-810; Coverage: 32%)
Sequence domains: Trypsin
Trypsin inhibitor 1
Molecule details ›
Chains: C, D
Length: 14 amino acids
Theoretical weight: 1.55 KDa
Source organism: Helianthus annuus
Expression system: Not provided
UniProt:
Length: 14 amino acids
Theoretical weight: 1.55 KDa
Source organism: Helianthus annuus
Expression system: Not provided
UniProt:
- Canonical: Q4GWU5 (Residues: 40-53; Coverage: 45%)
