› 6qai

X-ray diffraction
1.66Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside 2-deoxyribosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 156 amino acids
Theoretical weight: 17.06 KDa
Source organism: Leishmania mexicana
Expression system: Escherichia coli
UniProt:
  • Canonical: E9AWJ0 (Residues: 1-155; Coverage: 100%)
Gene name: LMXM_23_1580
Sequence domains: Nucleoside 2-deoxyribosyltransferase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand TRS 3 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: C2
Unit cell:
a: 80.209Å b: 46.265Å c: 87.987Å
α: 90° β: 115.06° γ: 90°
R-values:
R R work R free
0.171 0.169 0.2
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Purine and pyrimidine salvage pathway in thermophiles: a valuable source of biocatalysts for the industrial production of nucleic acid derivatives.
Del Arco et al. (2018)
5 other articles

1 mention without citation

N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs.
Acosta et al. (2020)