› 6qe2

X-ray diffraction
1.75Å resolution

Crystal structure of Paleococcus ferrophilus monoacylglycerol lipase.

Released:
DOI: 10.2210/pdb6qe2/pdb
PDB entry 6qe2 coloured by chain, front view.
PDB entry 6qe2 coloured by chain, side view.
PDB entry 6qe2 coloured by chain, top view.
Source organism: Palaeococcus ferrophilus
Primary publication:
Structure and Dynamics of an Archeal Monoglyceride Lipase from Palaeococcus ferrophilus as Revealed by Crystallography and In Silico Analysis.
Labar G, Brandt N, Flaba A, Wouters J, Leherte L
Biomolecules 11 (2021)
PMID: 33916727

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167323 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monoacylglycerol lipase Chains: A, B
Molecule details ›
Chains: A, B
Length: 283 amino acids
Theoretical weight: 31.45 KDa
Source organism: Palaeococcus ferrophilus
Expression system: Escherichia coli BL21

Ligands and Environments

2 bound ligands:
Ligand GOL 2 x GOL
Ligand LDA 2 x LDA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 2
Spacegroup: C2
Unit cell:
a: 120.6Å b: 75.46Å c: 85.44Å
α: 90° β: 128.29° γ: 90°
R-values:
R R work R free
0.172 0.171 0.198
Expression system: Escherichia coli BL21

Quick links

Citations

1 citations in other articles

Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket.
Grininger et al. (2021)

1 mention without citation

Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex.
Pinotsis et al. (2023)