› 6qk6

Solution NMR

Solution Structure of the Cd-loaded form of a Metallothionein from Helix Pomatia

Released:
DOI: 10.2210/pdb6qk6/pdb
PDB entry 6qk6 coloured by chain, ensemble of 20 models, front view.
PDB entry 6qk6 coloured by chain, ensemble of 20 models, side view.
PDB entry 6qk6 coloured by chain, ensemble of 20 models, top view.
Source organism: Helix pomatia
Primary publication:
The Solution Structure and Dynamics of Cd-Metallothionein from Helix pomatia Reveal Optimization for Binding Cd over Zn.
Beil A, Jurt S, Walser R, Schönhut T, Güntert P, Palacios Ò, Atrian S, Capdevila M, Dallinger R, Zerbe O
Biochemistry 58 4570-4581 (2019)
PMID: 31633358

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadmium-metallothionein Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 6.64 KDa
Source organism: Helix pomatia
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P33187 (Residues: 1-66; Coverage: 100%)

Ligands and Environments

1 bound ligand:
Ligand CD 6 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Zinc finger structure determination by NMR: Why zinc fingers can be a handful.
Neuhaus D. (2022)
8 other articles

1 mention without citation

Evolution of Cd2+ and Cu+ binding in Helix pomatia metallothioneins.
Valsecchi et al. (2023)