› 6qs9

X-ray diffraction
2.8Å resolution

Bovine Serum Albumin in complex with Ketoprofen

Released:
DOI: 10.2210/pdb6qs9/pdb
PDB entry 6qs9 coloured by chain, front view.
PDB entry 6qs9 coloured by chain, side view.
PDB entry 6qs9 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Biohybrid Electrospun Membrane for the Filtration of Ketoprofen Drug from Water.
Castagna R, Donini S, Colnago P, Serafini A, Parisini E, Bertarelli C
ACS Omega 4 13270-13278 (2019)
PMID: 31460455

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136192 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chains: A, B
Molecule details ›
Chains: A, B
Length: 607 amino acids
Theoretical weight: 69.4 KDa
Source organism: Bos taurus
Expression system: Bos taurus
UniProt:
  • Canonical: P02769 (Residues: 1-607; Coverage: 100%)
Gene name: ALB
Sequence domains: Serum albumin family

Ligands and Environments

2 bound ligands:
Ligand JGE 2 x JGE
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: C2
Unit cell:
a: 212.486Å b: 44.374Å c: 142.715Å
α: 90° β: 113.24° γ: 90°
R-values:
R R work R free
0.218 0.215 0.272
Expression system: Bos taurus

Quick links

Citations

3 citation in other articles

Ketoprofen-Based Ionic Liquids: Synthesis and Interactions with Bovine Serum Albumin.
Ossowicz et al. (2019)
2 more

10 mentions without citation

Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
Czub et al. (2020)
9 more